Are Omega-3 fatty acids effective in treating heart diseases?

Question

The Synthesis of Omega-3 fatty Acid involves the Na-channel which is a membrane protein that conducts Na-ions  through a cell’s plasma membrane.  Depending on the trigger that opens the Na-channel, it’s called voltage gated (when the channel opens because of a voltage-change) or ligand gated (when the binding of a ligand opens the channel). The Na-channel mediates fast depolarization and conduct electrical impulses throughout nerve, muscle and heart, thereby enabling co-ordination of higher processes ranging from locomotion to cognition.

Docosahexaenoic acid (Omega-3)(DHA) suppresses  the activity of Na-channels. That’s the main reason why Omega 3 lowers the heart rate and causes many of the beneficial effects. Clinical and experimental data indicate that changes in the expression of voltage-gated sodium channels play a key role in the pathogenesis of neuropathic pain and that drugs that block these channels are potentially therapeutic. Clinical and experimental data also suggest that changes in voltage-gated sodium channels may play a role in inflammatory pain, and here too sodium-channel blockers may have therapeutic potential.

Omega-3 capsules

Omega-3 fatty acids

Omega-3 (DHA) fatty acids are considered to contain essential nutrients in preventing and managing heart disease

Omega-3 fish oil contains both docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Omega-3 fatty acids are essential nutrients that are important in preventing and managing heart disease.

Findings show omega-3 fatty acids may help to:

  • Lower blood pressure
  • Reduce triglycerides
  • Slow the development of plaque in the arteries
  • Reduce the chance of abnormal heart rhythm
  • Reduce the likelihood of heart attack and stroke
  • Lessen the chance of sudden cardiac death in people with heart disease

The American Heart Association (AHA) recommends that everyone eats fish (particularly fatty, coldwater fish) at least twice a week. Salmon, mackerel, herring, sardines, lake trout, and tuna are especially high in omega-3 fatty acids. While foods are your best bet for getting omega-3s in your diet, fish oil supplements are also available for those who do not like fish. The heart-healthy benefits of regular doses of fish oil supplements are unclear, so talk to your doctor to see if they’re right for you. If you have heart disease or high triglyceride levels, you may need even more omega-3 fatty acids. Ask your doctor if you should take higher doses of fish oil supplements to get the omega-3s you need.

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Credit:

www.scienceforums.net by Itoero
www.webmd.com

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Marie 2 years 1 Answer 793 views 0

Answer ( 1 )

  1. Some people are concerned that mercury or other contaminants in fish may outweigh its heart-healthy benefits. However, when it comes to a healthier heart, the benefits of eating fish usually outweigh the possible risks of exposure to contaminants. Find out how to balance these concerns with adding a healthy amount of fish to your diet.

    Fish contain unsaturated fatty acids, which, when substituted for saturated fatty acids such as those in meat, may lower your cholesterol. But the main beneficial nutrient appears to be omega-3 fatty acids in fatty fish.

    Omega-3 fatty acids are a type of unsaturated fatty acid that may reduce inflammation throughout the body. Inflammation in the body can damage your blood vessels and lead to heart disease and strokes. Omega-3 fatty acids may decrease triglycerides, lower blood pressure slightly, reduce blood clotting, decrease stroke and heart failure risk and reduce irregular heartbeats. Eating at least one to two servings a week of fish, particularly fish that’s rich in omega-3 fatty acids, appears to reduce the risk of heart disease, particularly sudden cardiac death.

    Credit:

    http://www.mayoclinic.com

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